Role of a liver-first approach for synchronous colorectal liver metastases

Table 1 Patients and tumor characteristics

Variable	No. of patients, n = 18
Patient characteristics
Age (yr), median (range)	54 (21-74)
Sex (male)	10
Pre-operative CEA level (μg/L), median (range)	26.3 (1-860)
Primary tumor site
Colon	2
Rectum	16
Symptoms caused by the primary tumor	13
Symptoms at the time of presentation
None	5
Rectal blood loss	7
Changes in bowel habits	6
AJCC T-stage on pathology
ypT1/ypT2	1
ypT3/ypT4	15
Lymph node status on pathology
ypN1/ypN2	14
ypN0	2
Hepatic metastasis
Size of largest metastasis (cm), median (range)	4 (2-16)
No. of metastasis, median (range)	4 (1-12)
Location (unilobular)	11
CRS score
< 3	2
≥ 3	16
Preoperative chemotherapy	14
Cycles, median (range)	3 (0-5)
Indication
Conversion	4
Locally advanced liver metastases	10
Regimens of preoperative chemotherapy
Oxaliplatin	10
Irinotecan	4
Cetuximab	4
Bevacizumab	2
Response of preoperative chemotherapy
PR	9
SD	4
PD	1