CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms

Table 1 Sociodemographic data of patients with sporadic colorectal cancer and controls n (%)

Variables	Control	Case	OR1	95%CI	P value
	(n = 400)	(n = 227)
Gender
Female	125 (31.3)	106 (46.7)	1.00 (reference)
Male	275 (69.7)	121 (53.3)	0.55	0.35-0.85	< 0.012
Age (mean)
< 62	350 (87.5)	105 (46.3)	1.00 (reference)
≥ 62	50 (12.5)	122 (53.7)	7.54	4.94-11.50	< 0.012
Tobacco consumption
Non-smokers	243 (60.8)	131 (57.7)	1.00 (reference)
Smokers	157 (39.2)	96 (42.3)	1.12	0.73-1.70	0.60
Alcohol consumption
Non-drinkers	218 (54.5)	127 (55.9)	1.00 (reference)
Drinkers	182 (45.5)	100 (44.1)	1.44	0.93-2.24	0.10

¹Odds ratio (OR) adjusted for age, gender, tobacco and alcohol consumption and polymorphisms in the dominant model;

²Significant P values < 0.05.