Angiopoietin-2/angiopoietin-1 as non-invasive biomarker of cirrhosis in chronic hepatitis C

Table 4 Comparisons among area under the curve of receiver operator characteristics from angiopoietin-2/angiopoietin-1 ratio and other non-invasive cirrhosis indices

Indices	AUC-ROC (95%CI)	Standard error	P value
Cirrhosis
Ang2/Ang1	0.810 (0.744-0.864)	0.040	-
AAR	0.643 (0.568-0.713)	0.050	0.010
APRI	0.887 (0.831-0.930)	0.025	0.106
FIB4	0.858 (0.798-0.906)	0.031	0.349
FI	0.805 (0.737-0.861)	0.047	0.995
FCI	0.750 (0.677-0.813)	0.053	0.372

Two-sided P values by De Long test. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; AAR: AST to ALT ratio; APRI: Aspartate aminotransferase-to-platelet ratio index; FIB4: Combination of biochemical values (platelets, ALT, AST) and age; FI: Fibrosis index; FCI: Fibrosis-cirrhosis index; AUC-ROC: Area under the curve of receiver operator characteristics; Ang1: Angiopoietin 1; Ang2: Angiopoietin 2.