Selective intestinal decontamination for the prevention of early bacterial infections after liver transplantation

Table 2 Characteristics of observational studies evaluating selective intestinal decontamination in liver transplant

Ref.	Type of study	SID regimen	Other antibiotics	Patients (n)		Patients with infection, n (%)		Period of observation posttransplantation (d)
				SID	Control	SID	Control
Gorensek et al[47], 1993	Prospective nonrandomized study with historical control	Norfloxacin and nistatin. Oropharyngeal paste (polymyxin, gentamicin, nystatin)	Metronidazole and Third-generation cephalosporins for 5 d	17	34	1 (5.9)1	18 (52.9)1	30
San-Juan et al[54], 2011	Prospective cohort study	Fluoroquinolones (norfloxacin or ciprofloxacin) 7 d	First- or second- or third generation cephalosporins, or antipseudomonal beta-lactams or glycopeptides	415	595	110 (26.5)	156 (26.21)	30
Sun et al[49], 2012	Retrospective uncontrolled study	Rifaximin	Cefotaxime and ampicillin for 24 h	30	80	7 (23.3)	23 (28.7)	90
Katchman et al[55], 2014	Retrospective cohort study	Colitin, gentamicin and nystatin	Cefazolin and metronidazole for 4 d	111	37	47 (42.7)	18 (46.8)	30

¹Only fungal and gram-negative infections reported. SID: Selective intestinal decontamination.