Serum adipokines might predict liver histology findings in non-alcoholic fatty liver disease

Figure 2 Receiver operating characteristic analysis to determine cut-off values of serum adipokines for differentiating histological severity. A: ROC curve of serum TNF-α, Visfatin, and IL-8 levels to differentiate steatosis degree of less than 33% from more advanced degrees of steatosis; B: ROC curve of serum IL-6 and IL-8 levels to differentiate lobular inflammation grade of less than two foci per high power field from more advanced grades of inflammation; C: ROC curve of serum Resistin, Hepcidin, and TNF-α levels to differentiate fibrosis stage of perisinusoidal or periportal from more advanced stages of fibrosis; D: ROC curve of serum TNF-α and IL-8 levels to differentiate steatohepatitis from simple fatty liver based on non-alcoholic fatty liver disease activity score. AUC: Area under curve; IL: Interleukin.