Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model

Figure 3 Immunohistochemical staining of VEGF in hepatocellular carcinoma in group A (TACE + GRGDSP loaded nanoparticles), group B (Control group 1, TACE + GRGDSP) and group C (Control group 2, TACE alone) (magnification × 100). A: VEGF expression in hepatocellular carcinoma in group A. B: Higher expression of VEGF in hepatocellular carcinoma was observed in group B than in group A; C: Higher immunohistochemical expression of VEGF in hepatocellular carcinoma was observed in group C than in groups A and B. VEGF: Vascular endothelial growth factor; TACE: Transarterial chemoembolization.