Serum adipokines might predict liver histology findings in non-alcoholic fatty liver disease

Table 3 Best cut-off values of serum adipokine levels to differentiate histological groups according to receiver operating characteristic analysis

Adipokine	Serum concentration	Sensitivity (%)	Specificity (%)
TNF-α (pg/mL)	2.13	74	58
Visfatin (ng/mL)	13.00	84	69
Interleukin 8 (pg/mL)	24.25	58	66
Cut-off values of serum adipokine levels to differentiate lobular inflammation grade of less than 2 foci per high power field from more advanced grades of inflammation.
Interleukin 6 (pg/mL)	3.70	94	70
Interleukin 8 (pg/mL)	13.00	77	74
Cut-off values of serum adipokine levels to differentiate perisinusoidal or periportal fibrosis from more advanced stages of fibrosis.
Resistin (mg/mL)	1.65	79	66
Hepcidin (ng/mL)	45.00	63	60
TNF-α (pg/mL)	2.44	67	70
Cut-off values of serum adipokine levels to differentiate steatohepatitis from simple fatty liver group based on non-alcoholic fatty liver disease activity score (NAS).
Interleukin 8 (pg/mL)	9.80	82	54
TNF-α (pg/mL)	2.44	71	81
Cut-off values of serum adipokine levels to differentiate steatosis degree of less than 33% from more advanced degrees of steatosis.

TNF-α: Tumor necrosis factor-alpha.