Growth hormone abolishes the negative effects of everolimus on intestinal wound healing

Figure 2 Hematoxylin and eosin staining from the anastomotic region. In the hematoxylin and eosin stained samples there were significant changes in anastomotical architecture in everolimus-treated animals, indicated by decreased cell density and reduced angiogenesis (B) which are indicators for granulation tissue. Simultaneous treatment with human growth hormone (hGH) showed more granulation tissue (C). A: Vehicle; B: Everolimus 3.0 mg/kg; C: Everolimus 3.0 mg/kg + hGH 2.5 mg/kg (magnification × 100).