Efficacy and safety of granulocyte, monocyte/macrophage adsorptive in pediatric ulcerative colitis

Table 2 ADAPT schedule of assessments

Visit	01	02	03	04	05	06	07	08	09	10
Day	-07	00	07	14	21	28
Week	-1	0	1	2	3	4	6	7	8	12
Apheresis		▲	▲	▲	▲	▲	(▲)	(▲)	(▲)
Physical examination	●									●
Endoscopy/EAI	●4									(●)5
PUCAI	●	●	●	●	●	●	●	●	●	●
Clin. Chemistry	●	●		●		●	●2	●2	●2	●
ESR	●	●		●		●	●2	●2	●2	●
Urinalysis	●	●		●		●	●2	●2	●2	●
Fecal sample	●
Coagulation	●					●	●2	●2	●2	●
Vital signs	●	●	●	●	●	●	●1	●1	●1	●
Concomitant medication	●	●	●	●	●	●	●	●	●	●
Adverse events	●3	●	●	●	●	●	●	●	●	●

¹Only for patients with treatment;

²Only for patients with last treatment;

³Only if an endoscopy was performed at post screening;

⁴The endoscopy should be done in the period between six weeks prior to screening and 5 d post screening visit;

⁵The timeframe for the optional endoscopy is 7 d prior and 7 d after Visit 10. PUCAI: Pediatric ulcerative colitis activity index.