Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-κB signaling in colorectal cancer cells

Figure 7 Integrin-linked kinase can promote epithelial-mesenchymal transition occurrence. A: Immunofluorescence revealed that E-cadherin fluorescence intensity significantly decreased in the pcDNA3.1-ILK group compared with the vector group; B: The difference between the vector group and pcDNA3.1-ILK group was statistically significant; C: Western blot revealed that vimentin, slug, and snail expression was increased, while E-cadherin expressions was reduced in the pcDNA3.1-ILK group; compared with the vector group. This experiment was repeated three times; D: The difference between the vector group and pcDNA3.1-ILK group was statistically significant. ILK: Integrin-linked kinase.