Comparison of scoring systems in predicting the severity of acute pancreatitis

Table 1 Characteristics of patients with severe acute pancreatitis n (%)

	Mild to moderately severe AP (n = 140)	Severe AP(n = 21)	P value
Age, yr	62.2 ± 16.5	63.4 ± 13.1	0.968
Male	84 (60.0)	18 (85.7)	0.023
BMI (kg/m2)	23.4 ± 4.4	23.9 ± 4.1	0.607
Hospital visit from symptom onset (d)	5.7 ± 12.8	3.3 ± 6.9	0.388
Etiology
Biliary	78 (55.7)	9 (42.8)	0.270
Alcoholic	26 (18.6)	10 (47.6)	0.030
Idiopathic	33 (23.6)	1 (4.8)	0.130
Others	3 (2.1)	1 (4.8)	0.472
Laboratory finding (initial)
Hematocrit (%)	39.1 ± 6.2	40.3 ± 7.4	0.422
Amylase (IU/L)	1687.9 ± 1415.4	1668.2 ± 1668.8	0.954
Lipase (IU/L)	1949.7 ± 1951.3	2108.2 ± 2750.3	0.744
AST (IU/L)	203.2 ± 240.4	362.6 ± 618.4	0.256
ALT (IU/L)	155.6 ± 182.1	184.7 ± 275.9	0.645
BUN (mg/dL)	14.5 ± 8.6	31.2 ± 32.9	0.031
Creatinine (mg/dL)	1.0 ± 0.5	2.2 ± 1.6	0.003
CRPi (mg/dL)	4.4 ± 6.8	6.9 ± 10.4	0.259
CRP24 (mg/dL)	9.0 ± 7.9	17.4 ± 12.7	0.026
Peripancreatic fluid collection	46 (32.9)	10 (47.6)	0.158
Duration of NPO (d)	4.3 ± 2.2	6.9 ± 5.1	0.038
Hospital stay (d)	8.4 ± 4.8	11.7 ± 6.2	0.008
Scoring systems
Ranson	2.7 ± 1.4	3.7 ± 1.4	0.005
BISAP	1.0 ± 0.8	1.9 ± 0.9	< 0.001
APACHE-II	6.5 ± 3.5	10.8 ± 4.8	< 0.001
CTSI	2.2 ± 1.4	3.5 ± 2.2	< 0.001
Mortality	1 (0.7)	2 (9.5)	0.005

Values are expressed as the mean ± SD. AP: Acute pancreatitis; BMI: Body mass index; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; CRPi: C-reactive protein measured at admission; CRP₂₄: C-reactive protein measured after 24 h; NPO: Nil per os; BISAP: Bedside Index for Severity in Acute Pancreatitis; APACHE-II: Acute Physiology and Chronic Health Evaluation-II; CTSI: Computed tomography severity index.