Clinical significance and usefulness of soluble heparin binding-epidermal growth factor in gastric cancer

Table 7 Logistic regression determination of the diagnostic accuracy of serum soluble heparin-binding epidermal growth factor-like growth factor compared with those of serum carcinoembryonic antigen for prediction of gastric cancer

Markers1	Cut-off point2	Sensitivity	Specificity
Serum sHB-EGF	0.38	76.1%	76.5%
Serum CEA	0.38	62.1%	51.8%
Serum sHB-EGF + CEA	0.38	77.3%	76.5%

¹Each marker is included as a linear term and evaluated as a panel from one to two markers combination.

²Cut-off point means the probability cut-off point to classify subjects as having gastric cancer (GC) or not in binary logistic regression. CEA: Carcinoembryonic antigen; sHB-EGF: Soluble heparin-binding epidermal growth factor-like growth factor.