Gene expression profiling of MYC-driven tumor signatures in porcine liver stem cells by transcriptome sequencing

Table 3 Genes upregulated by MYC in PICM-19-CSCs

Gene ID	Gene abbreviation	Function	log2 ratio
CH242-278B18.2	GNAS Complex, porcine-specific	Unknown	10.25
NFKB1	Nuclear factor κB	Inflammation	8.94
SEMA3F	Semaphorin 3F	Cell signaling	8.27
NME1-NME2	NME1-NME2 read-through	Inflammation	8.22
SERPINA1	Serpin protease inhibitor, clade A1	Inflammation	8.17
VLDLR	Very low density lipoprotein receptor	Metabolism	8.01
APOE	Apolipoprotein E	Metabolism	7.57
ITGA3	Integrin, alpha 3	Migration, Cell adhesion, Invasion	7.41
IGF2BP2	Insulin-like growth factor 2 mRNA binding protein 2	Gene regulation	7.33
MT-ATP6	Mitochondrial ATP synthase 6	Metabolism	7.21
HIF1A	Hypoxia-inducible factor 1α	Angiogenesis	7.12
APOA1	Apolipoprotein A1	Metabolism	7.06
ITGB7	Integrin, beta 7	Cell adhesion	7.03
NKAIN1	Na+/K+ transporting ATPase	Ion transport	7.00
FGG	Fibrinogen gamma chain	Cell adhesion	6.79
CTSB	Cathepsin B	Carcinogenesis	6.74
NTN1	Netrin 1	Inflammation	6.65
JUP	Junction plakoglobin	Cell adhesion	6.61
PLG	Plasminogen	Cell proliferation	6.60
MT-ND2	Mitochondrial NADH dehydrogenase 2	Metabolism	6.37
SERPINA3-2	Serpin protease inhibitor, clade A3-2	Inflammation	6.31
RBP4	Retinol binding protein 4	Metabolism	6.18
FTL	Ferritin, light polypeptide	Iron metabolism	6.08
DUSP4	Dual specificity phosphatase 4	Cell proliferation	6.02
MT-CO1	Mitochondrial cytochrome c oxidase I	Inflammation	6.00