Characteristics of symptomatic reflux episodes in Japanese proton pump inhibitor-refractory non-erosive reflux disease patients

Figure 3 Total mixed liquid-gas reflux episodes and symptoms above the proximal margin of the lower esophagogastric junction at each impedance site. The 113 distal reflux episodes were significantly more frequent (60.1%) than 35 proximal reflux (39.9%) (P = 0.0047, distal reflux episodes vs proximal reflux). LES: Lower esophagogastric junction.