Basic Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Dec 7, 2015; 21(45): 12822-12834
Published online Dec 7, 2015. doi: 10.3748/wjg.v21.i45.12822
Figure 5
Figure 5 The p38MAPK/mTOR pathway was involved in autophagy activation by heat shock pretreatment in mesenchymal stem cells. Western blot showed that p-p38MAPK was upregulated and p-mTOR was downregulated by heat shock pretreatment (HSP) in mesenchymal stem cells. The p38MAPK inhibitor, SB203580, counteracted the effects of HSP on LC3-II, beclin 1 and p-p38MAPK expression. The data represent the results of three separate experiments.