Basic Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Dec 7, 2015; 21(45): 12822-12834
Published online Dec 7, 2015. doi: 10.3748/wjg.v21.i45.12822
Figure 4
Figure 4 Inhibition of autophagy abrogated the effects of heat shock pretreatment on apoptosis reduction in mesenchymal stem cells exposed to H2O2 treatment. A: Flow cytometry indicated that 3-MA significantly increased the apoptotic rate in heat shock pretreatment (HSP)-treated mesenchymal stem cells; B: Western blot showed that 3-MA significantly increased Bax and cytochrome C expression, and decreased Bcl-2, LC3-II and beclin 1 expression. The data represent the results of three separate experiments. aP < 0.05, bP < 0.01 compared with the control group; dP < 0.01 compared with the HSP2h group.