Retinoic acid receptor α promotes autophagy to alleviate liver ischemia and reperfusion injury

Figure 5 Retinoic acid receptor α mediates autophagy through the Foxo3a/p-Akt/Foxo1 pathway. A: Western blot assessment of RARα, Foxo3a, p-Akt, Foxo1, and β-actin expression levels. B: Western blot analysis of Beclin1, LC3I/II, p62 and β-actin expression levels. Mean ± SD, n = 3-5/group, ^aP < 0.05 vs the DMSO group; ^bP < 0.05 vs the H₂O₂ group. RARα: Retinoic acid receptor α; ATRA: All-trans retinoic acid.