Clinical characteristics of hepatoduodenal lymph node metastasis in gastric cancer

Table 1 Comparison of the clinicopathological features between patients with and without hepatoduodenal lymph node metastasis n (%)

	n	HDLN metastasis		Univariate	Multivariate
		Positive	Negative	P value	OR (95%CI)	P value
Total	276	26	250
Sex
Male	186	16 (62)	170 (68)
Female	90	10 (38)	80 (32)	0.509	-
Age (yr)
< 65	134	10 (38)	124 (50)
≥ 65	142	16 (62)	126 (50)	0.277	-
Tumor location
U	64	2 (8)	62 (25)
M and L	212	24 (92)	188 (75)	0.029	5.88 (1.61-38.1)	0.005
CA 19-9 (U/mL)
< 10	132	9 (35)	123 (49)
≥ 10	144	17 (65)	127 (51)	0.153	-
CEA (ng/mL)
< 3	195	16 (62)	179 (72)
≥ 3	81	10 (38)	71 (28)	0.295	-
Histopathological type
Differentiated	135	10 (38)	125 (50)
Undifferentiated	141	16 (62)	125 (50)	0.260	-
Venous invasion
(-)	173	12 (46)	161 (64)
(+)	103	14 (54)	89 (36)	0.072	-
Lymphatic invasion
(-)	105	3 (12)	102 (42)
(+)	171	23 (88)	148 (58)	0.002	-
Tumor size (mm)
< 45	119	5 (19)	114 (46)
≥ 45	157	21 (81)	136 (54)	0.007	-
T category
T1 and T2	127	3 (12)	124 (50)
T3 and T4	149	23 (88)	126 (50)	< 0.0001	4.45 (1.28-21.3)	0.017

HDLN: Hepatoduodenal lymph node; CEA: Carcinoembryonic antigen; CA 19-9: Carbohydrate antigen 19-9; U: Upper gastric body; M: Middle gastric body; L: Lower gastric body.