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©The Author(s) 2015.
World J Gastroenterol. Sep 28, 2015; 21(36): 10375-10384
Published online Sep 28, 2015. doi: 10.3748/wjg.v21.i36.10375
Published online Sep 28, 2015. doi: 10.3748/wjg.v21.i36.10375
Figure 5 Downregulation of CYP450 in Recql5-deficient mice after lipopolysaccharide/D-Gal administration.
WT and Recql5-deficient (Recql5-/-) mice were injected with lipopolysaccharide (LPS)/D-Gal or saline, and livers were harvested at 6 h (n = 4-7 per group). RNA was isolated from the livers, and mRNA levels of CYP2A4 (A), CYP2A5 (B), CYP2B9 (C), and CYP2B10 (D) were measured by real-time quantitative PCR and normalized to GAPDH mRNA levels. aP < 0.05, bP < 0.01, WT vs Recql5-/-.
- Citation: Liao WQ, Qi YL, Wang L, Dong XM, Xu T, Ding CD, Liu R, Liang WC, Lu LT, Li H, Li WF, Luo GB, Lu XC. Recql5 protects against lipopolysaccharide/D-galactosamine-induced liver injury in mice. World J Gastroenterol 2015; 21(36): 10375-10384
- URL: https://www.wjgnet.com/1007-9327/full/v21/i36/10375.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i36.10375