Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury

Table 7 Hepatoprotective effects of broccoli sprout extract on D-GalN-induced liver injury

Marker	Control		BSEx		D-GalN		D-GalN + BSEx
	Mean	SD	Mean	SD	Mean	SD	Mean	SD
Body weight (g)	237.31	10.49	235.13	16.38	224.30	11.14	225.39	10.76
Body weight gain after i.p (g)	1.85	1.32	3.50	0.97	-7.74a	2.42	-4.10b	3.67
Liver weight (g)	10.38	0.32	11.16	1.25	7.40a	0.60	8.32b	1.33
Liver/body	0.044	0.001	0.048	0.002	0.032a	0.001	0.036b	0.005
AST (IU/L)	55.73	8.66	66.30	24.08	12465.63a	3223.97	4820.05b	3094.93
ALT (IU/L)	11.12	1.01	12.47	3.48	3936.46a	777.52	1808.95b	1014.04
GST activity (U/g tissue)	87.92	10.42	109.43	23.19	53.15a	8.14	98.04	15.75
TBARS (μmol/g tissue)	418.96	33.06	442.34	41.10	543.81c	45.35	495.42d	54.46

^aP < 0.05 vs Control, BSEx, D-GalN + BSEx;

^bP < 0.05 vs Control, BSEx, D-GalN;

^cP < 0.05 vs Control, BSEx;

^dP < 0.05 vs Control. BSEx: Broccoli sprout extract; AST: Aspartate transaminase; ALT: Alanine transaminase; GSH: Hepatic glutathione; GST: Glutathione-S-transferase.