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Copyright ©The Author(s) 2015.
World J Gastroenterol. Sep 7, 2015; 21(33): 9693-9706
Published online Sep 7, 2015. doi: 10.3748/wjg.v21.i33.9693
Table 5 Risk factors and proposed screening recommendations for gastric cancer
Risk factorsRisk for developing gastric cancerRecommendationFirst author
Helicobacter pylori infectionOdds ratio (OR): 2.3High risk area - mass screening possible benefitHuang, 1998
Low risk area - mass screening not cost-effective
Pernicious anemiaStandardized incidence ratio: 5Screening by upper endoscopy (UE) recommendedKokkola, 1998
Partial gastrectomy15-24 yr, RR = 9.4Screening by UE recommendedLundegardh, 1988
25-46 yr, RR = 55.6Tersmette, 1991
Familial adenomatous polyposisNot availableScreening by UE recommendedAlexander, 1989
Hereditary nonpolyposis colorectal cancerNot availableScreening by UE recommendedAarnio, 1997
Positive family history of gastric cancerOR: 2.5-5.1HP eradication +/- UE screeningYatsuya, 2004
Chen, 2004