Comparison of effects of obesity and non-alcoholic fatty liver disease on incidence of type 2 diabetes mellitus

Table 2 Incidence of type 2 diabetes mellitus and Cox hazards regression analysis in subjects with different baseline non-alcoholic fatty liver disease and body mass index levels

Group	n	T2DM	Incidence rate (%)1	RR (95%CI)	RR2 (95%CI)
Non-alcoholic fatty liver disease
No	3379	135	4.1	1	1
Yes	1412	245	17.4	4.492 (3.640-5.542)	3.367 (2.367-4.266)
Body mass index (kg/m2)
< 24	2999	166	5.5	1	1
About 24	1249	137	11	2.023 (1.614-2.537)	1.274 (0.997-1.629)
About 28	488	77	15.8	2.954 (2.254-3.870)	1.554 (1.140-2.091)
Age (yr)
< 30	291	5	1.7	1	1
About 30	722	17	2.4	1.350 (0.498-3.658)	1.044 (0.379-2.875)
About 40	1033	54	5.2	3.043 (1.217-7.607)	1.853 (0.736-4.665)
About 50	1135	114	10	6.021 (2.459-14.743)	3.136 (1.270-7.747)
About 60	1555	190	12.2	7.469 (3.074-18.152)	4.344 (1.772-10.651)
Gender
F	3149	86	5.4	1	1
M	1587	294	9.3	1.748 (1.374-2.222)	1.327 (1.025-1.720)
SBp
< 140	3672	237	6.5	1	1
≥ 140	1064	143	13.4	2.164 (1.759-2.664)	1.462 (1.139-1.877)
Alanine aminotransferase
< 40	4094	303	7.4	1	1
≥ 40	642	77	12	1.628 (1.268-2.091)	1.522 (1.165-1.988)
Total	4736	380	8

¹P < 0.001 by Log Rank (Mantel-Cox) test, showing differences in the incidence rate between the groups;

²RR adjusted for age, sex, blood pressure, lipids, alanine aminotransferase, uric acid, and creatinine. T2DM: Type 2 diabetes mellitus.