Interferon-free regimens for the treatment of hepatitis C virus in liver transplant candidates or recipients

Table 2 Studies of interferon-free regimens for treatment of hepatitis C virus positive liver transplant candidates

Ref.	No. of patients	Severity of liver disease based on CP score	Antiviral scheme (duration)	Virological response
Curry et al[16]	61	≤ 7	SOF + RBV (for 48 wk or until LT)	69% (12 wk after LT)
Afdhal et al[17]	40	5-10	SOF + RBV (48 wk)	100% and 93% for Child class A and B, respectively at 24 wk under treatment
Gane et al[18]	20	7-9	SOF + Ledipasvir ± RBV(12 wk)	89%
Flamm et al[19]	108	Decompensated cirrhosis (CP score range: 7-12)	Ledipasvir/SOF + RBV(12 or 24 wk)	87% and 89% (for 12 and 24 wk, respectively)

CP: Child-Pugh; SOF: Sofosbuvir; RBV: Ribavirin.