Presence of c.3956delC mutation in familial adenomatous polyposis patients from Brazil

Table 2 Mutations in the APC gene: Relationship between genotype and phenotype in patients with familial adenomatous polyposis

Families	Exon	Codon	Mutation	Phenotype1	Ref.
			Frameshift mutations
FAP1	15	1061	c.3183_3187delACAAA	Intermediate	Ficari et al[18], Jarry et al[19]
FAP2	15	1309	c.3927_3931delAAAGA	Severe	Miyoshi et al[20], Jarry et al[19]
FAP5	15	1309	c.3921_3925delAAAAG	Severe	Miyaki et al[21], Mulkens et al[22]
FAP1-FAP5	15	1319	c.3956delC	Severe	Miyaki et al[21]

¹According to Nieuwenhuis et al[16].