Portal vein thrombosis in cirrhosis: Controversies and latest developments

Table 1 Key studies of portal vein thrombosis and liver transplantation

	Number of patients	Prevalence PVT, n (%)	PVT characteristics	Outcomes
Englesbe et al[65]	22291 (2001-2007)	897 (4.02)	Not described	PVT was not predictive of waiting list mortality (HR = 0.90, P = 0.23)
				PVT was predictive of post-transplant mortality (HR = 1.32, P = 0.02)
Sringeri et al[61]	1491 (2000-Aug 2012)	119 (8.0)	Not described	Prolonged theatre timea, increased blood transfusion rates1. No difference mortality up-to 140 mo
Ravaioli et al[13]	889 (1998-2008)	91 (10.2)	Partial 51 (56%)	No difference 1 yr (85% vs 86%) and 5 yr (68% vs 73%) survival between PVT and non-PVT subjects
			Complete 40 (44%)	Survival improved significantly for patients with complete PVT in the second era (2003-2008) (57% vs 89% at 1 yr1)
Yerdel et al[15]	779 (1987-1996)	63 (8.1)	Grade 1: 24,	Reduced 5 yr survival between PVT and non-PVT subjects (65.3% vs 76.3%1)
			Grade 2: 23,
			Grade 3: 6,	But improved 5 yr survival from 1st to 2nd era in all patients (from 72% to 83%1)
			Grade 4: 10

¹The P value is < 0.05. PVT: Portal vein thrombosis.