Basic Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jan 14, 2015; 21(2): 465-474
Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.465
Figure 4
Figure 4 Butein treatment decreased mucosal expression of phosphorylated signal transducer and activator of transcription 3 and matrix metalloproteinase-9 expression in interleukin-10-/- mice. A: Immunohistochemical staining for phosphorylated signal transducer and activator of transcription 3 (pSTAT3) and matrix metalloproteinase (MMP)-9 detected nuclei of epithelial cells or stromal cells of interleukin (IL)-10-/- mice (black arrows); B: Western blot analysis revealed reduced pSTAT3 protein expression in intestinal epithelial cells of butein-treated IL-10-/- mice (n = 3). PBS: Phosphate-buffered saline.