Review
Copyright ©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 7, 2014; 20(9): 2127-2135
Published online Mar 7, 2014. doi: 10.3748/wjg.v20.i9.2127
Table 2 Gender differences in alcoholic liver disease
Alcoholic liver disease (hepatic steatosis, alcoholic hepatitis, cirrhosis)
Hepatic damage faster in F than M
RR to develop cirrhosis 7 in M and 17 in F
RR to develop alcoholic liver disease 3, 7 in M and 7, 3 in F
F more susceptible to damage by alcohol than M: higher haematic concentration of ethanol in F than M: major risk of hepatitis progression toward cirrohosis (even after an absentation from alcohol) in F than M
Differences in corporal structures (content of corporal water), different enzymatic activity (gastric ADH expression and activity), hormonal