Helicobacter pylori infection and extragastric disorders in children: A critical update

Table 3 Follow-up and platelet response to Helicobacter pylori eradication therapy among children with chronic idiopathic thrombocytopenic purpura

Study	Follow-up	Bacterialeradication	PLT count (× 109/L) among treatedH. pylori-positive with eradication success/No. of children	PLT count (× 109/L) among treatedH. pylori-positive with eradication failure/No. of children	PLT count (× 109/L) among untreatedH. pylori-positive/No. of children	PLT count (× 109/L) amongH. pylori-negative/No. of children
Jaing et al[95] 2003, Taiwan	6 mo	9/9	> 150/2	-	-	50-99/4
			100-150/2			< 50/9
			50-99/1
			< 50/4
Hayashi et al[97] 2005, Japan	1 yr	1/1	> 150/1	-	NR	> 100/2
						NR/6
Yetgin et al[98] 2005, Turkey	1 yr	9/11	< 50/9	< 50/2	-	NR
Loffredo et al[99] 2007, Italy	1 yr	7/8	NA	NA	-	< 100/31
Neefjes et al[100] 2007, Netherlands	6-9 mo	3/3	≥ 100/3	-	-	51 ± 39.6/30
Wu et al[101] 2007, Taiwan	NR	-	-	-	88.2 ± 89.5/61	64.9 ± 75.8/161
						132.7 ± 74.7/92
Bisogno et al[102] 2008, Italy	6-50 mo	8/8	> 150/3	-	-	> 100/3
			< 50/5			50-99/8
						< 50/5
Hamidieh et al[103] 2008, Iran	6-11 mo	4/4	50-99/2	-	-	NR
			< 50/2
Treepongkaruna et al[105] 2009, Thailand	6 mo	7/7	> 100/1	-	> 100/1	-
			< 100/6		< 100/7
Ferrara et al[104] 2009, Italy	1 yr	8/8	≥ 150/6	-	-	50-99/7
			100-149/2			< 50/9
Russo et al[106] 2011, Italy	1 yr	33/37	> 150/7	< 50/4	-	-
			50-149/6
			< 50/20

Results are given as mean plus or minus standard deviation, or as median (range), unless otherwise noted.

¹On therapy with high-dose methylprednisolone;

²On therapy with intravenous immunoglobulin. PLT: Platelet; H. pylori: Helicobacter pylori; NR: Not reported.