Review
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 28, 2014; 20(48): 18092-18103
Published online Dec 28, 2014. doi: 10.3748/wjg.v20.i48.18092
Table 3 Authors’ recommendations for fluid replacement in predicted severe or severe acute pancreatitis
ParameterRecommendation
Fluid resuscitationNecessary: the earlier the resuscitation, the better the outcome
Type of fluidColloids and/or crystalloids: Among crystalloids, lactate Ringer’s better than normal salineUse colloids especially when albumin < 2.0 g/dL or hematocrit < 35%
Amount of fluidTotal fluid in first 24 h: between 3 and 4 L, Not to exceed 4 L
Rate of infusionInitial bolus 1000 mL over one hour followed by 3 mL/kg per hour (200 mL/h) for 24-48 h
MonitoringUrine output > 0.5 mL/kg/h, hematocrit = 25% to 35%, drop in BUNCVP: Not good for monitoring due to third space loss and hypoalbuminemia
Duration of resuscitation24-48 h, until signs of volume depletion disappear