Achieving the best bowel preparation for colonoscopy

Table 2 Comparison studies including low-volume solutions

Ref.	Comparison	n	Conclusion
DiPalma et al[27]	PEG 4 L vs PEG 2 L+ 20 mg bisacodyl	93/93	PEG 2 L + bisacodyl is more tolerable
Jansen et al[28]	PEG 4 L	91/91/102/86/91	PEG 2 L + ascorbate equal to PEG 4 L solution in cleansing quality, taste and compliance
	vs PEG 4 L + with 20 mL simethicone		NaP inferior to PEG 4 L in bowel cleansing quality
	vs PEG 2 L + ascorbate
	vs PEG 2 L + ascorbate with 20 mL simethicone vs NaP
Pontone et al[29]	PEG 4 L vs PEG 2 L + ascorbate	72/72	Residual stool score significantly lower with PEG 4 L
Corporaal et al[30]	PEG 4 L vs PEG 2 L + ascorbate	149/158	PEG + ascorbate less effective in right colon cleansing
Marmo et al[31]	PEG 4 L vs PEG 2 L + ascorbate	435/433	PEG + ascorbate as effective as high-volume PEG-electrolyte solution but has superior palatability
Ell et al[32]	PEG 4 L vs PEG 2 L + ascorbate	153/155	PEG + ascorbate same efficacy and safety, better tolerance
Gentile et al[33]	PEG 4 L vs PEG 2 L + ascorbate	60/60	Similar efficacy
Repici et al[34]	PEG 2 L + ascorbate vs PEG 2 L + citrate + bisacodyl	202/203	PEG 2 L + citrate + bisacodyl more effective for bowel cleansing
Bitoun et al[35]	PEG 2 L + ascorbate vs NaP	169/171	PEG + ascorbate at least as efficacious as NaP, comparable efficacy, better tolerability profile
Rex et al[22]	4 L PEG SF-ELS vs NaP	68/68	NaP superior bowel cleansing, similar tolerability
Renaut et al[37]	MC-SP vs NaP	32/41	MC-SP better tolerated, similar cleansing effectiveness
Choi et al[38]	NaP vs magnesium citrate + NaP (45 mL)	79/80	Both similar effectiveness
Schmidt et al[39]	MC-SP vs NaP	182/190	MC-SP better tolerance, similar cleansing effectiveness
Hookey et al[40]	MC-SP + bisacodyl vs MC-SP vs NaP	105/109/101	MC-SP + bisacodyl better colon cleansing in the right colon compared with two other groups
Tjandra et al[42]	MC-SP vs NaP	120/102	NaP better cleansing
Katz et al[41]	MC-SP vs PEG 2 L + 10 mg bisacodyl tablets	300/303	Similar quality of cleansing
Rex et al[43]	PEG 2 L + bisacodyl 5 mg vs picosulphate	304/297	Picosulphate is better for cleansing bowel and tolerated

MC-SP: Magnesium citrate and sodium picosulfate; NaP: Sodium phosphate; PEG: Polyethylene glycol; SF-ELS: Sulfate-free electrolyte; SPS: Sodium picosulphate.