Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma

Table 1 Associations and comparisons between phosphatidylinositol 3-kinase CB expression and clinicopathological factors in 208 rectal adenocarcinoma patients receiving preoperative radiotherapy

Parameter		No. of cases	PIK3CB expression		P value
			Low	High
Sex	Male	120	37	83	0.619
	Female	88	30	58
Age in years	< 65	140	47	93	0.547
	≥ 65	68	20	48
TH in cm	< 5	74	14	60	0.002
	≥ 5	134	53	81
PreTNM	II	29	9	20	0.945
1(18)	III	161	51	110
BMI	0	11	2	9	0.300
	1	105	29	76
	2	76	29	45
	3	16	5	11
LVI	Negative	21	4	17	0.222
	Positive	187	63	124
Diff.	ypCR	11	3	8	0.562
1(1)	G1-2	146	41	105
	G3-4	50	18	32
ypT	T0	8	6	2	0.043
	T1	11	4	7
	T2	55	20	35
	T3	134	37	97
ypN	N0	122	36	86	0.608
	N1	55	20	35
	N2	31	11	20
TRG	1 (G1-2)	32	29	3	0.000
	2 (G3)	79	26	53
	3 (G4-5)	97	12	85

¹Lack of number of patients. 0: < 18.4; 1: 18.5-23.9; 2: 24.0-27.9; 3: ≥ 28.0. TH: Tumor height; BMI: Body mass index; PIK3: Phosphatidylinositol 3-kinase; LVI: Lymph vessel invasion; TRG: Tumor regression grade.