Gut microbiota and metabolic syndrome

doi:10.3748/wjg.v20.i43.16079

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 20, Issue 43

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (23184)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-5) series.

Item

Count

PDF

2625

WORD

511

HTML

17107

Tables (1-5)

165

Sum=20408

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1291

Download

1485

Sum=2776

Nov 21, 2014 (publication date) through Apr 24, 2024

Times Cited of This Article

Times Cited (367)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Gastroenterol. Nov 21, 2014; 20(43): 16079-16094
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16079

Table 4 Studies conducted on animal models showing effects of prebiotics on metabolic disorders

Studied subjects	Prebiotic	Duration of treatment	Effects	Ref.
Wistar rats	OFS	50 d	↓Body weight, food intake, fat mass, serum triglycerides, ghrelin	[126]
Wistar rats	OFS	50 d	↑GLP-1	[126]
Wistar rats	OFS	6 wk	↓Food intake, serum glucose and insulin	[127]
Wistar rats	OFS	6 wk	↑GLP-1, glucose tolerance	[127]
HFD fed mice	OFS	13 wk	↑Bifidobacterium, glucose tolerance	[105]
HFD fed mice	OFS	13 wk	↓Pro-inflammatory cytokines, endotoxemia	[105]
C57B/6J mice	OFS	4 wk	↓LPS, hepatic inflammatory and oxidative stress markers, intestinal permeability	[128]
C57B/6J mice	OFS	4 wk	↑GLP-2	[128]
C57B/6J mice	OFS	8 wk	↓Firmicutes/Bacteroides ratio, fat mass, oxidative stress, low grade inflammation	[129]
C57B/6J mice	OFS	8 wk	↑Glucose tolerance, GLP-1 and leptin sensitivity	[129]
C57B/6J mice	AX	4 wk	↑Bacteroides, Prevotella, Roseburia, Bifidobacterium spp	[130]
			Improvement of gut barrier function	[130]
			↓Adipocyte size, fatty acids storage, body weight, serum cholesterol, insulin resistance, low grade inflammation	[131]
Lean and obese JCR:LA.cp rats	Inulin-OFS	10 wk	↓Firmicutes, food intake	[131]
Lean and obese JCR:LA.cp rats	Inulin-OFS	10 wk	↑Bacteroides, Bifidobacterium, satiety hormones

OFS: Oligofructose; GLP-1: GLucagon-like peptide-1; LPS: Lipopolysaccharides; GLP-2: Glucagon-like peptide-2; AX: Arabinoxylose; HFD: High-fat diet.

Citation: Festi D, Schiumerini R, Eusebi LH, Marasco G, Taddia M, Colecchia A. Gut microbiota and metabolic syndrome. World J Gastroenterol 2014; 20(43): 16079-16094
URL: https://www.wjgnet.com/1007-9327/full/v20/i43/16079.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i43.16079