Topic Highlight
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 21, 2014; 20(39): 14272-14279
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14272
Figure 2
Figure 2 Diagnostic algorithm for proton pump inhibitor refractory patients with typical reflux symptoms. Endoscopy should be performed in uninvestigated patients and in patients with previous detection of reflux esophagitis or Barrett’s esophagus. Impedance-pH monitoring should be performed during ongoing proton pump inhibitor (PPI) treatment. SAP: Symptom association probability; SI: Symptom index.