Topic Highlight
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Oct 21, 2014; 20(39): 14272-14279
Published online Oct 21, 2014. doi: 10.3748/wjg.v20.i39.14272
Table 2 Side-effects and complications of proton pump inhibitors
Headache (< 2%)
Diarrhea (< 2%)
Malabsorption of magnesium, calcium, vitamin B12, iron (doubtful)
Increased risk of Clostridium difficile colitis in antibiotic users (doubtful)
Increased risk of pneumonia (doubtful)
Acute interstitial nephritis (extremely rare)
Drug-drug interactions (doubtful)
Accelerated progression of Helicobacter pylori gastritis (doubtful)
Formation of gastric fundic gland polyps (potentially harmful when > 1 cm)