Serum immunoglobulin A concentration is a reliable biomarker for liver fibrosis in non-alcoholic fatty liver disease

Table 1 Clinical and biochemical data of the study population (mean ± SD)

Variable	Casesn = 50	Controlsn = 54	P value
Age (yr)	41.44 ± 13.04	32.28 ± 8.35	0.000
Sex (n)	M:32	M:29	0.287
	F:18	F:25
Weight (kg)	79.14 ± 12.3	64.61 ± 10.96	0.000
Height (cm)	167.64 ± 9.48	166.34 ± 24.79	0.730
BMI (kg/m²)			0.000
< 25	23.79 ± 0.8	22.7 ± 1.8
25-29.9	27.8 ± 1.3	25.2 ± 0.3
≥ 30	33.2 ± 3.6	-
Abdomen (cm)	92.80 ± 13.49	78.55 ± 13.11	0.001
Hip (cm)	100.05 ± 10.06	87.18 ± 13.01	0.001
ALT (U/mL)	79.66 ± 35.93	20.07 ± 8.00	0.000
AST (U/mL)	47.62 ± 18.78	19.93 ± 5.19	0.000
AST/ALT ratio	0.64 ± 0.19	1.09 ± 0.35	0.000
ALP (mg/dL)	209.10 ± 75.21	-	-
Albumin (mg/dL)	4.45 ± 0.47	-	-
FBS (mg/dL)	102.74 ± 22.57	-	-
TG (mg/dL)	210.14 ± 104.81	-	-
Cholesterol (g/dL)	201.76 ± 37.01	-	-
HDL (mg/dL)	46.22 ± 10.49	-	-
LDL (mg/dL)	119.50 ± 39.42	-	-
IgA (mg/dL)	324.20 ± 111.63	318.111 ± 82.49	0.751

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; HDL: High-density lipoprotein; HDL: High-density lipoprotein; IgA: Immunoglobulin A.