Role of ERK-MAPK signaling pathway in pentagastrin-regulated growth of large intestinal carcinoma

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Sep 21, 2014 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2014; 20(35): 12542-12550
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12542

Table 4 Comparison of proliferation index and apoptotic rates between the experimental groups and control group (mean ± SD)

Group	n	PI			AR
Group	n	PI (%)	F	P value	AR (%)	F	P value
Control group	5	27.72 ± 5.00			2.53 ± 0.36
Pentagastrin group	5	37.54 ± 5.17^a	7.59	0.01	1.91 ± 0.42^a	6.50	0.01
Proglumide group	5	27.36 ± 2.68^c			2.79 ± 0.45^c
Pentagastrin + proglumide group	5	27.31 ± 5.76^c			2.41 ± 0.30^c

^aP < 0.05 vs control group;

^cP < 0.05 vs pentagastrin group. AR: Apoptosis rate; PI: Proliferation index.

Citation: Mao JD, Wu P, Huang JX, Wu J, Yang G. Role of ERK-MAPK signaling pathway in pentagastrin-regulated growth of large intestinal carcinoma. World J Gastroenterol 2014; 20(35): 12542-12550
URL: https://www.wjgnet.com/1007-9327/full/v20/i35/12542.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i35.12542