Occupational exposures and colorectal cancers: A quantitative overview of epidemiological evidence

Table 2 Pooled estimates for colorectal cancer, by industrial branch and study design

ISIC	Industrial branch	Cohort studies		Other study design2		All
		(95%CI)		(95%CI)		(95%CI)
		Crude RR	Adjusted RR3	Crude RR	Adjusted RR3	Crude RR	Adjusted RR3
1	Crop and animal production	0.86	-	2.6	-	0.86	-
		(0.81-0.91)		(1.12-6.02)		(0.76-0.97)
3	Fishing and aquaculture1	0.98	-	-	-	0.98	-
		(0.70-1.10)				(0.87-1.10)
8	Other mining and quarrying	0.8	-	0.84	-	0.83	-
		(0.70-0.92)		(0.77-0.92)		(0.77-0.89)
10	Manufacture of food products	1.21	-	-	-	1.21	-
		(0.76-1.92)				(0.76-1.92)
11	Manufacture of beverages	1.29	-	-	-	1.29	-
		(1.19-1.40)				(1.19-1.40)
13	Manufacture of textile	2.82	0.73	1.34	-	2	-
		(0.19-41.78)	(0.07-7.96)	(1.12-1.61)		(0.83-4.86)
15	Manufacture of leather and related products	1.7	-	-	-	1.7	-
		(1.24-2.34)				(1.24-2.34)
16	Manufacture of wood and of products of wood and cork	1.65	-	-	-	1.65	-
		(0.60-4.58)				(0.60-4.58)
19	Manufacture of coke and refined petroleum products1	1.21	-	-	-	1.21	-
		(0.69-2.12)				(0.69-2.12)
20	Manufacture of chemicals and chemical products	1.27	-	-	-	1.27	-
		(0.92-1.76)				(0.92-1.76)
22	Manufacture of rubber and plastics products	1.3	-	1.37	-	1.3	-
		(0.94-1.79)		(0.86-2.18)		(0.98-1.71)
23	Manufacture of other non-metallic mineral products	1.25	-	-	-	1.25	-
		(0.85-1.85)				(0.85-1.85)
24	Manufacture of basic metals	1.32	-	-	-	1.32	-
		(1.07-1.65)				(1.07-1.65)
26	Manufacture of computer, electronic and optical products1	-	-	2.14	-	2.14	-
				(1.02-4.50)		(1.02-4.50)
28	Manufacture of machinery and equipment nec1	2.2	-	-	-	2.2	-
		(1.03-4.72)				(1.03-4.72)
29	Manufacture of motor vehicles1	1.27	-	-	-	1.27	-
		(0.89-1.82)				(0.89-1.82)
31	Manufacture of furniture1	1.5	-	-	-	1.5	-
		(1.21-1.87)				(1.21-1.87)
33	Repair and installation of machinery and equipment	1.4	-	-	-	1.4	-
		(1.07-1.84)				(1.07-1.84)
37	Sewerage1	1.14	-	-	-	1.14	-
		(0.47-2.77)				(0.47-2.77)
72	Scientific research and development1	1.18	-	-	-	1.18	-
		(0.77-1.82)				(0.77-1.82)
84	Public administration and defence	0.97	0.87	-	-	0.97	0.87
		(0.62-1.52)	(0.58-1.30)			(0.62-1.52)	(0.58-1.30)
96	Other personal service activities1	1.09	-	-	-	1.09	-
		(0.98-1.21)				(0.98-1.21)
-	All industrial branches combined	1.18	1.18	1.36	1.13	1.19	1.12
		(1.08-1.30)	(1.08-1.30)	(0.94-1.97)	(0.81-1.57)	(1.09-1.33)	(1.03-1.23)
	Heterogeneity (I2)	84.1%		87.9%		84.3%

¹Only one study;

²Case-control studies and meta-analyses;

³Duval and Tweedie trim and fill method. RR: Relative risk; ISIC: International Standard Industrial Classification.