Non-pulmonary allergic diseases and inflammatory bowel disease: A qualitative review

Table 1 Recommendations for probiotic use

Clinical condition	Effectiveness	Organism
Diarrhea
Infectious-adult-treatment	A	Saccharomyces boulardi, LGG
Infectious-childhood- treatment	A	LGG. Lactobacillus reuteri
Prevention of infection	B	S. boulardii, LGG
Prevention of AAD	A	S. boulardii, LGG, L. casei, L. bulgaricus, S. thermophilus
Treatment of recurrent CDAD	B	S. boulardii, LGG
Prevention of CDAD	B	LGG, S. boulardii
IBD
Pouchitis
Preventing and maintaining remission	A	VSL#3
Induce remission	C	VSL#3
Ulcerative colitis
Inducing remission	C	Escherichia coli Nissle, VSL#3
Maintenance	C	E. coli Nissle, VSL#3
Crohn's	C	E. coli Nissle, S. boulardii, LGG
IBS	B	Bifidobacterium infantis
IBS	C	Bifidobacterium animalis, VSL#3, Lactobacillus plantarum
Immune response	A	LGG, Lactobacillus acidophilus, L. plantarum, Bifidobacterium lactis, Lactobacillus johnsonii
Allergy
Atopic eczema assoc. with cow milk allergy
Treatment	A	LGG, B. lactis
Prevention	A	LGG, B. lactis
Radiation enteritis	C	VSL#3, L. acidophilus
Vaginosis and vaginitis	C	L. acidophilus, LGG, L. reuteri

Reproduced with permission from reference Floch et al[31]. An ‘‘A’’ recommendation is based on strong, positive, well-conducted, controlled studies in the primary literature, not abstract form; A ’‘B’’ recommendation is based on positive, controlled studies but the presence of some negative studies; A ‘‘C’’ recommendation is based on some positive studies. IBD: Inflammatory bowel disease; LGG: Lactobacillus GG; S. boulardii: Saccharomyces boulardii.