Update on imaging of Peutz-Jeghers syndrome

Table 1 Summary of studies throughout the literature dealing with magnetic resonance enterography and the evaluation of polyps in patients with Peutz-Jeghers syndrome

Studies	Design	Number of PJS patients who underwent MR enteroclysis/enterography	Type of MR-enterography	Comparative methodused to evaluate polyps	Results of the study	Impact of MR-enterography in the management of PJS patients
Gupta et al[24]	Prospective	19	Enterography per os	VCE	13 MR detected polyps (11-15 mm) with MR vs 11 with VCE 10 MR detected polyps (> 15 mm) vs 7 with VCE	MR enterography less prone to missing large polyps
Maccioni et al[27]	Retrospective	8	Enterography per os	Enteroscopy/surgical laparoscopic enteroscopy/surgery	142 MR detected polyps (28 > 15 mm) 187 enteroscopy-detected polyps (30 > 15 mm)	Excellent concordance between MR enterography and enteroscopy for the detection of large polyps (93%)
Caspari et al[28]	Prospective	4	Enterography per os	VCE	Equivalent detection rates for polyps > 15 mm with VCE and MR Better detection of small polyps with VCE Polyps smaller than 5 mm were exclusively observed with VCE	Identical detection of large polyps with the two methods Better determination of polyp location and size with MR imaging
Schulmann et al[31]	Prospective	4	Enteroclysis	VCE/ push-enteroscopy/esophagogastroduodenoscopy/surgery	Similar findings of MR enteroclysis compared to VCE in 3 out of 4 patients Large polyps (up to 30 mm) missed by MR enteroclysis in one patient	VCE is at least equivalent to MR enteroclysis Small number of patients

MR: Magnetic resonance; PJS: Peutz-Jeghers syndrome; VCE: Videocapsule endoscopy.