Review
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Jul 7, 2014; 20(25): 8092-8101
Published online Jul 7, 2014. doi: 10.3748/wjg.v20.i25.8092
Table 1 Overview of gastric cancer detection and treatment via traditional methods compared with metabolomics
Cancer detection state/stageTraditional methodsMetabolomics (biomarkers)Ref.
DiagnosisEndoscopy, biopsyLactic acid, butanedioic acid, malic acid, citric acids, pyruvic acid, 3-hydroxypropionic acid, serine, proline[91,93,100,101]
PrognosisRadiotherapy, chemotherapy surgeryValine, isoleucine, serine, 3-indoxyl sulfate, hippurate, citrate[96,99,102]
MetastasisComputed tomography (CT) scanning, endoscopic ultrasonography (EUS), positron emission tomography (PET)Sarcosine, alanine, proline, serine, myo-inositol, glycerol[90,91,98,103]
Chemosensitivity of drugsMTT chemosensitivity assay1-acyl-lysophosphatidylcholines and polyunsaturated fatty acids[75,104]