Protective effect of bone marrow mesenchymal stem cells in intestinal barrier permeability after heterotopic intestinal transplantation

Figure 2 Graft histopathology at different time points after heterotopic intestinal transplantation (HE staining, × 200). A: Normal intestine with normal villous architecture and glands in group A; B: Intestinal mucosa degradation and hemorrhage of the lamina propria, ulceration, decreased ratio of villus height and crypt height, aggravated lymphocyte infiltration, partial gland epithelial necrosis in group B at day 5 after operation; D: There were decreased intestinal mucosal villi with mild deformity and interstitial infiltration of inflammatory cells; E: The condition was aggravated 7 d after heterotopic intestinal transplantation, and there was epithelial degeneration, intestinal wall thinning and necrosis, and interstitial inflammatory cell infiltration in great quantities; C, F: Recovery of the damaged mucosa in group A at (C) day 5 and (F) day 7.