Comparative study of esomeprazole and lansoprazole in triple therapy for eradication of Helicobacter pylori in Japan

Table 4 Adverse effects in each therapy

Adverse events	Esomeprazole therapy				Lansoprazole therapy
	G1	G2	G3	Total, %	G1	G2	G3	Total, %
Diarrhea	32	3	1	36, 27%	33	7	1	41, 31%
Bitter taste	13	3	0	16, 12%	14	2	0	16, 12%
Nausea	1	0	0	1, 0.7%	1	0	0	1, 0.7%
Vomiting	2	0	1	3, 2.2%	0	0	0	0, 0%
Eruption	1	2	0	3, 2.2%	2	1	0	3, 2.2%
Headache	0	0	0	0, 0%	2	0	0	2, 1.5%
Fatigue	1	0	0	1, 0.7%	0	0	0	0, 0%
Appetite loss	2	1	0	3, 2.2%	1	0	0	1, 0.7%
Stomatitis	0	0	0	0, 0%	1	0	0	1, 0.7%
Cheilitis	0	0	0	0, 0%	2	0	0	2, 1.5%
Thirst	2	0	0	2, 1.5%	0	0	0	0, 0%
Belch	1	0	0	1, 0.7%	0	0	0	0, 0%
Bad breath	1	0	0	1, 0.7%	0	0	0	0, 0%
Sore throat	1	0	0	1, 0.7%	0	0	0	0, 0%
Joint paint	1	0	0	1, 0.7%	0	0	0	0, 0%
Leg edema	0	0	0	0, 0%	1	0	0	1, 0.7%
Chest discomfort	2	0	0	2, 1.5%	0	0	0	0, 0%
Floating	1	0	0	1, 0.7%	0	0	0	0, 0%
Abdominal wind	1	0	0	1, 0.7%	0	0	0	0, 0%
Constipation	2	0	0	2, 1.5%	2	0	0	2, 1.5%
Pruritus ani	0	0	0	0, 0%	1	0	0	1, 0.7%
Total	64	9	2	75, 56%	60	10	1	71, 53%