An updated review of gastric cancer in the next-generation sequencing era: Insights from bench to bedside and vice versa

doi:10.3748/wjg.v20.i14.3927

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 14, 2014; 20(14): 3927-3937
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.3927

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Figure 1 Genetic and epigenetic alterations in gastric carcinogenesis. The model for gastric carcinogenesis is presented based on genetic and epigenetic alterations. Methylation of the genes in blue appears to be involved in an epigenetic field defect. H. pylori: Helicobacter pylori; MSI: Microsatellite instability; EBV: Epstein-Barr virus; CIMP: CpG island methylator phenotype.

Citation: Yamamoto H, Watanabe Y, Maehata T, Morita R, Yoshida Y, Oikawa R, Ishigooka S, Ozawa SI, Matsuo Y, Hosoya K, Yamashita M, Taniguchi H, Nosho K, Suzuki H, Yasuda H, Shinomura Y, Itoh F. An updated review of gastric cancer in the next-generation sequencing era: Insights from bench to bedside and vice versa. World J Gastroenterol 2014; 20(14): 3927-3937
URL: https://www.wjgnet.com/1007-9327/full/v20/i14/3927.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i14.3927

Yamamoto H, Watanabe Y, Maehata T, Morita R, Yoshida Y, Oikawa R, Ishigooka S, Ozawa SI, Matsuo Y, Hosoya K, Yamashita M, Taniguchi H, Nosho K, Suzuki H, Yasuda H, Shinomura Y, Itoh F. An updated review of gastric cancer in the next-generation sequencing era: Insights from bench to bedside and vice versa. World J Gastroenterol 2014; 20(14): 3927-3937 [PMID: 24744582 DOI: 10.3748/wjg.v20.i14.3927]

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