Abstracts Open Access
Copyright ©The Author(s) 1996. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 15, 1996; 2(Suppl1): 50-50
Published online Sep 15, 1996. doi: 10.3748/wjg.v2.iSuppl1.50
Levels of motilin change in patients with gastric ulcer: Analysis of 32 cases
Ya-Min Wang, 1st People's Hospital of Nantong Jiangsu, Nantong, Jiangsu Province, China
Author contributions: The author solely contributed to the work.
Received: November 12, 1995
Revised: April 22, 1996
Accepted: May 13, 1996
Published online: September 15, 1996

Abstract

AIM: The patients with gastric ulcer often have abnormal gastric emptying. Motilin can stimulate the movement of stomach. It is studied that the motilin change before and after treatment in the patients with gastric ulcer.

METHODS: There are 32 cases diagnosed by endoscopy. Plasmic motilin was tested before and two weeks after treatment. 18 cases were tested again 2 mo later. The plasmic motilin was tested by motilin RIA kit.

RESULTS: Compared with controls, there were no significant in plasmic motilin before treatment. But the levels of motilin returned to normal 2 mo later.

CONCLUSION: Motilin release is affected by the volume of stomach, acidity in the duodenum and movement of stomach, recovery of pyloric function and excitation of vagus. These factors also stimulate the release of motilin. After the ulcer is healed, the levels of motilin in patients with gastric ulcer can be used as an objective index to evaluate the effect of treatment.

Key Words: Motilin, Gastric ulcer



Footnotes

Original title: China National Journal of New Gastroenterology (1995-1997) renamed World Journal of Gastroenterology (1998-).

E- Editor: Liu WX

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