Dietary-suppression of hepatic lipogenic enzyme expression in intact male transgenic mice

Figure 1 Farnesyl pyrophosphate synthase, fatty acid synthase and 3-hydroxyl-3-methyl-glutaryl CoA reductase activity, mRNA levels in the four groups of treatment. A: Activity levels in the four groups of treatment. ^aP < 0.05 vs SD group (one-way analysis of variance and Tukey’s Multiple Comparison Test). Data are expressed as mean ± SE; B: mRNA levels in the four groups of treatment. ^aP < 0.05 vs SD group (one-way analysis of variance and Tukey’s Multiple Comparison Test); ^cP < 0.05 vs OO group (Tukey’s Multiple Comparison Test). Data expressed as n molecules mRNA target gene/n molecules mRNA β-actin. SD: Standard diet; OO: Olive oil; LOVA: Olive oil plus lovastatin; OR: Olive oil plus orlistat; FPP: Farnesyl pyrophosphate; FAS: Fatty acid synthase; HMGCoAR: 3-hydroxyl-3-methyl-glutaryl CoA reductase.