Association between TNF-α and IL-1β genotypes vs Helicobacter pylori infection in Indonesia

Table 3 Association between Helicobacter pylori infection and allele of interleukin 1β, interleukin 4, interleukin 8, CD14, tumor necrosis factor-α, tyrosine-protein phosphates non-receptor type 11 in Indonesian people n (%)

Allele	H. pylori (+)n= 66	H. pylori (-)n= 522	OR1	95%CI
IL-1β T-31C
T	33 (50.0)	247 (47.3)	ref
C	33 (50.0)	275 (52.7)	1.10	0.70-1.73
IL-4 T-33C
T	46 (69.7)	370 (70.9)	ref
C	20 (30.3)	152 (29.1)	0.95	0.58-1.56
IL-8 T-251A
T	39 (59.1)	310 (59.4)	ref
A	27 (40.9)	212 (40.6)	0.99	0.62-1.57
CD14 C-159T
C	32 (48.5)	261 (50.0)	ref
T	34 (51.5)	261 (50.0)	0.95	0.60-1.49
TNF-α T-1031C
T	38 (57.6)	345 (66.1)	ref
C	28 (42.4)	177 (33.9)	0.73	0.46-1.15
PTPN11 G/A at intron 3
G	49 (74.2)	395 (75.7)	ref
A	17 (25.8)	127 (24.3)	0.94	0.56-1.57

¹Odds rate with CI adjusted for age and sex by logistic regression model. H. pylori: Helicobacter pylori; IL: Interleukin; PTPN11: Tyrosine-protein phosphates non-receptor type 11.