Preoperative biliary drainage in patients with hilar cholangiocarcinoma undergoing major hepatectomy

Table 4 Studies including resections for hilar cholangiocarcinoma with and without preoperative biliary drainage n (%)

Ref.	Year	Country	Design	Type of PBD	Surgical procedures for included patients	PBD	n	Morbidity	P value	Mortality	P value
Su et al[10]	1996	China	Retro	PTCD	CR and PR	Yes	33	17 (51.5)	NS	5 (15.2)	NS
						No	16	6 (37.5)		0
Takada et al[37]	1996	Japan	Retro	PTCD	CR	Yes	24	NA	-	3 (12.5)	NS
						No	12	NA		6 (50)
Hochwald et al[19]	1999	United States	Pro	PTCD	CR and PR	Yes	42	36 (85.7)	0.045	2 (4.8)	NS
				EBD		No	29	19 (65.5)		4 (14.3)
Figueras et al[31]	2000	Spain	Retro	PTCD	CR	Yes	11	11 (100)	NS	1 (9)	NS
						No	9	6 (66)		2 (22.2)
Parks et al[36]	2000	United Kingdom	Retro	PTCD	CR and PR	Yes	20	11 (55)	NS	1 (5)	NS
				EBD		No	27	11 (40.7)		1 (3.7)
Gerhards et al[5]	2000	The Netherlands	Retro	PTCD	CR	Yes	93	59 (63)	NS	16 (17)	NS
				EBD		No	18	13 (72)		3 (17)
Dinant et al[33]	2006	The Netherlands	Retro	PTCD	CR	Yes	83	56 (67.5)	NS	14 (16.7)	NS
				EBD		No	14	6 (42.9)		2 (14.3)
Li et al[32]	2009	China	Retro	PTCD	CR and PR	Yes	55	20 (36.3)	NS	4 (7.3)	NS
						No	56	16 (28.6)		5 (8.9)
Ferrero et al[18]	2009	Italy	Retro	PTCD	CR	Yes	30	21 (70)	NS	1 (3)	NS
				EBD		No	30	19 (63)		3 (10)
				SD
Ercolani et al[34]	2010	Italy	Retro	PTCD	CR and PR	Yes	44	25 (56.8)	NS	NA	-
				EBD		No	7	2 (28.5)		NA
El-Hanafy et al[20]	2010	Egypt	Retro	PTCD	CR	Yes	46	27 (58.6)	0.001	5 (10.8)	NS
				EBD		No	54	11 (20.3)		3 (5.5)
Yu et al[35]	2012	China	Retro	PTCD with bile re-infusion	CR and PR	Yes	48	14 (29.2)	0.036	1 (2.1)	NS
						No	39	20 (51.3)		2 (5.1)
Farges et al[14]	2013	France and Belgium	Retro	PTCD	CR	Yes	180	123 (68.3)	NS	17 (9.4)	NS
				EBD		No	186	128 (68.8)		22 (11.8)
Present study		China	Retro	PTCD	CR	Yes	32	17 (53.1)	NS	3 (9.4)	NS
				EBD		No	46	27 (58.7)		2 (4.3)
				SD

Retro: Retrospective; Pro: Prospective; PBD: Preoperative biliary drainage; PTCD: Percutaneous transhepatic cholangio-drainage; EBD: Endoscopic biliary drainage; SD: Surgical drainage; CR: Curative resection; PR: Palliative resection; NA: Not available; NS: Not significant.