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Copyright ©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 28, 2013; 19(40): 6721-6729
Published online Oct 28, 2013. doi: 10.3748/wjg.v19.i40.6721
Table 1 Genes implicated as having coding variants in inflammatory bowel disease
Gene symbolDescriptionRef.
ADAM17Disintegrin and metalloproteinase domain-containing protein 17[57]
ATG16L1Autophagy related 16-like 1[7]
C1orf106Chromosome 1 open reading frame 106[46]
CARD9Caspase recruitment domain family, member 9[46]
CUL2Cullin 2[46]
DLG5Discs-large 5[58]
HEATR3HEAT repeat containing 3[59]
IL10RA and BInterleukin-10 receptor[34]
IL18RAPInterleukin 18 receptor accessory protein[46]
IL23RInterleukin 23 receptor[45]
LRBALPS-responsive vesicle trafficking, beach and anchor containing[60]
MDR1Multi-drug resistance 1[61]
MUC19Mucin 19, oligomeric
NCF2Neutrophil cytosolic factor 2[62]
NDP52Antigen nuclear dot 52 kDa Protein[55]
NOD2Nucleotide-binding oligomerization domain containing 2[3,4]
PRDM1PR domain containing 1, with Zinc finger domain[55]
PTN22Protein tyrosine phosphatase, non-receptor type 22 (lymphoid)[46]
SLC22A4Solute carrier family 22 (organic cation/ergothioneine transporter), member 4[63]
TNFRSF6BTumor necrosis factor receptor superfamily, member 6b, decoy[47]