Bisacodyl plus split 2-L polyethylene glycol-citrate-simethicone improves quality of bowel preparation before screening colonoscopy

Table 1 Characteristics of the two polyethylene glycol bowel preparations

	PEG-CS	4-L PEG
Active ingredients	Bisacodyl, PEG, citrates, simethicone	PEG, sodium sulphate
Product description	4 sachets; each containing PEG 4000 60.7 g, sodium citrate 1.066 g, citric acid 1.25 g, simethicone 80 mg	8 sachets; each containing PEG 4000 29.5 g and sodium sulphate 2.843 g
Total volume	2-L	4-L
Electrolytes	Sodium chloride, potassium chloride	Sodium bicarbonate, sodium chloride, potassium chloride
Osmolality (mOsmol/kg)	293	288
Mixed with	Water	Water
Diet prior to colonoscopy	Clear liquid after starting solution intake	Clear liquid after starting solution intake
Timing of intake	1-L of solution at 19:00 the day prior to procedure 1-L of solution at 7:00 the day of the exam	3-L of solution at 17:00 the day prior to procedure 1-L of solution at 7:00 the day of the exam
Additional agents	15 mg bisacodyl (3 tablets) at 16.00 the day prior to procedure

PEG: Polyethylene glycol; PEG-CS: PEG with citrates and simethicone.