Diagnostic value of AFP-L3 and PIVKA-II in hepatocellular carcinoma according to total-AFP

Table 4 Stepwise multiple linear regression analysis using dependent variables α-fetoprotein-L3 and prothrombin induced by vitamin K absence-II

Variable	AFP-L3		PIVKA-II
	βcoefficient	P value	βcoefficient	P value
AFP	0.839	< 0.001		NS
Tumor size	0.190	0.002		NS
AST		NS	0.550	< 0.001
Total bilirubin		NS	0.336	< 0.001
Platelet		NS	0.566	0.001
Albumin		NS	-0.674	< 0.001

AFP: α-fetoprotein; PIVKA-II: Prothrombin induced by vitamin K absence-II; AST: Aspartate aminotransferase; NS: Not significant.